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MPZL1 Protein (His tag)

MPZL1 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318794
  • Antigène Voir toutes MPZL1 Protéines
    MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))
    Type de proteíne
    Recombinant
    Origine
    • 6
    • 2
    • 1
    Humain
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette MPZL1 protéine est marqué à la His tag.
    Fonction
    Recombinant Human MPZL1 Protein (His Tag)
    Séquence
    Ser36-Val162
    Attributs du produit
    Recombinant Human Myelin Protein P0-like 1 is produced by our Mammalian expression system and the target gene encoding Ser36-Val162 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product MPZL1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène
    MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))
    Autre désignation
    MPZL1 (MPZL1 Produits)
    Synonymes
    MPZL1 Protein, MPZL1b Protein, PZR Protein, PZR1b Protein, PZRa Protein, PZRb Protein, 1110007A10Rik Protein, myelin protein zero like 1 Protein, myelin protein zero-like 1 Protein, MPZL1 Protein, Mpzl1 Protein
    Sujet

    Background: Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.

    Synonym: Myelin protein zero-like 1, isoform CRA_b,cDNA FLJ78597, highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1), transcript variant 1, mRNA ,cDNA, FLJ96614, Homo sapiens myelin protein zero-like 1 (MPZL1), Mrna

    Poids moléculaire
    15.2 kDa
    UniProt
    O95297
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