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PI3 Protein (His tag)

PI3 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318425
  • Antigène Voir toutes PI3 Protéines
    PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
    Type de proteíne
    Recombinant
    Origine
    • 9
    • 1
    Humain
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette PI3 protéine est marqué à la His tag.
    Fonction
    Recombinant Human PI3/Elafin Protein (His Tag)
    Séquence
    Ala23-Gln117
    Attributs du produit
    Recombinant Human Elafin is produced by our Mammalian expression system and the target gene encoding Ala23-Gln117 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PI3 Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
    Autre désignation
    PI3/Elafin (PI3 Produits)
    Synonymes
    ESI Protein, SKALP Protein, WAP3 Protein, WFDC14 Protein, cementoin Protein, trappin-2 Protein, TRAPPIN-2 Protein, elafin Protein, peptidase inhibitor 3 Protein, peptidase inhibitor 3, skin-derived (SKALP) Protein, PI3 Protein
    Sujet

    Background: Elafin is a secreted protein. Elafin consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize Elafin covalently to specific sites on extracellular matrix proteins. It is shown that Elafin can be used as a biomarker for graft versus host disease of the skin. Elafin is expressed in the skin during wound healing through activation of the epidermal growth factor receptor. Elafin may prevent elastase-mediated tissue proteolysis.

    Synonym: Elafin, Elastase-Specific Inhibitor, ESI, Peptidase Inhibitor 3, PI-3, Protease inhibitor WAP3, Skin-Derived Antileukoproteinase, SKALP, WAP Four-Disulfide Core Domain Protein 14, PI3, WAP3, WFDC14

    Poids moléculaire
    11.0 kDa
    UniProt
    P19957
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