Peroxiredoxin 2 Protein (PRDX2) (His tag)

N° du produit ABIN7317603

Détail du produit

Antigène: Peroxiredoxin 2 (PRDX2)

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette Peroxiredoxin 2 protéine est marqué à la His tag.

Fonction: Recombinant Human Peroxiredoxin 2/PRDX2 Protein (His Tag)(Active)

Séquence: Met 1-Asn 198

Attributs du produit: A DNA sequence encoding the human PRDX2 (P32119) (Met 1-Asn 198) was expressed, with a polyhistidine tag at the N-terminus.

Pureté: > 92 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Measured by its ability to reduce H2O2.The specific activity is >300 pmoles/min/μg.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Peroxiredoxin 2 (PRDX2)

Autre désignation: Peroxiredoxin 2/PRDX2 (PRDX2 Produits)

Synonymes: NKEF-B Protein, NKEFB Protein, PRP Protein, PRX2 Protein, PRXII Protein, PTX1 Protein, TDPX1 Protein, TPX1 Protein, TSA Protein, AL022839 Protein, Band-8 Protein, NkefB Protein, PrxII Protein, TDX1 Protein, TPx Protein, TPx-B Protein, TR Protein, Tdpx1 Protein, Torin Protein, nkefb Protein, prx-2 Protein, prx2 Protein, prxii Protein, tdpx1 Protein, tpx1 Protein, peroxiredoxin 2 Protein, peroxiredoxin 2 L homeolog Protein, PRDX2 Protein, Prdx2 Protein, prdx2.L Protein

Sujet:

Background: Peroxiredoxin-2, also known as Natural killer cell-enhancing factor B, NKEF-B, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, PRDX2 and NKEFB, is a cytoplasm protein which belongs to the ahpC / TSA family. Peroxiredoxin-2 / PRDX2 contains one thioredoxin domain. Peroxiredoxin-2 / PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-2 / PRDX2 is not able to receive electrons from glutaredoxin. It may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-2 / PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The Peroxiredoxins / Prx are a family of peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups ( PRDX1,PRDX2, PRDX3, PRDX4, PRDX5, PRDX6 ) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.

Synonym: HEL-S-2a;NKEF-B;NKEFB;PRP;PRX2;PRXII;PTX1;TDPX1;TPX1;TSA

Poids moléculaire: 24 kDa

UniProt: P32119