PLA2G12B Protein (His tag)

N° du produit ABIN7320191

Détail du produit

Antigène: PLA2G12B (Phospholipase A2, Group XIIB (PLA2G12B))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette PLA2G12B protéine est marqué à la His tag.

Fonction: Recombinant Mouse PLA2G12B/PLA2G13 Protein (His Tag)

Séquence: Met 1-Leu 195

Attributs du produit: A DNA sequence encoding the mouse PLA2G12B (NP_076019.2) (Met 1-Leu 195) was expressed, with a C-terminal polyhistidine tag.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM NaAc, 100 mM NaCl, pH 5.0

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: PLA2G12B (Phospholipase A2, Group XIIB (PLA2G12B))

Autre désignation: PLA2G12B/PLA2G13 (PLA2G12B Produits)

Synonymes: wu:fb26d02 Protein, wu:fb99g06 Protein, wu:fc91d12 Protein, zgc:111897 Protein, zgc:56487 Protein, zgc:77746 Protein, MGC79728 Protein, GXIIB Protein, GXIIIsPLA2 Protein, PLA2G13 Protein, 2010002E04Rik Protein, Pla2g13 Protein, hlb218 Protein, phospholipase A2, group XIIB Protein, phospholipase A2 group XIIB Protein, pla2g12b Protein, PLA2G12B Protein, Pla2g12b Protein

Sujet:

Background: Group XIIB secretory phospholipase A2-like protein, also known as Group XIII secretory phospholipase A2-like protein, GXIII sPLA2-like, sPLA2-GXIIB, GXIIB, PLA2G13 and PLA2G12B, is a secreted protein which belongs to the phospholipase A2 family. PLA2G12B / PLA2G13 is strong expression in liver, small intestine and kidney. Mammalian secretory phospholipase A2s ( sPLA2s ) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via the release of arachidonic acid from membrane phospholipids or the binding to specific membrane receptors. Phospholipases A2 / PLA2 are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids. Phospholipases A2 / PLA2 are commonly found in mammalian tissues as well as insect and snake venom. Venom from both snakes and insects is largely composed of melittin, which is a stimulant of Phospholipases A2 / PLA2. Due to the increased presence and activity of Phospholipases A2 / PLA2 resulting from a snake or insect bite, arachidonic acid is released from the phospholipid membrane disproportionately. As a result, inflammation and pain occur at the site.

Synonym: 2010002E04Rik;Fksg71;hlb218;Pla2g13

Poids moléculaire: 21 kDa

NCBI Accession: NP_076019