PLXDC1 Protein (His tag)

N° du produit ABIN7318914

Détail du produit

Antigène: PLXDC1 (Plexin Domain Containing 1 (PLXDC1))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette PLXDC1 protéine est marqué à la His tag.

Fonction: Recombinant Human TEM7/PLXDC1 Protein (His Tag)

Séquence: Leu19-Thr426

Attributs du produit: Recombinant Human Plexin Domain-Containing Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu19-Thr426 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Threhalose, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: PLXDC1 (Plexin Domain Containing 1 (PLXDC1))

Autre désignation: TEM7/PLXDC1 (PLXDC1 Produits)

Synonymes: PLXDC1 Protein, TEM3 Protein, TEM7 Protein, 2410003I07Rik Protein, AI848450 Protein, Tem7 Protein, Arl12 Protein, plexin domain containing 1 Protein, PLXDC1 Protein, Plxdc1 Protein

Sujet:

Background: Plexin Domain-Containing Protein 1 (PLXDC1) is a single-pass type I membrane protein that belongs to the plexin family. Secreted PLXDC1 is localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. PLXDC1 is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. It can detect in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. PLXDC1 interacts with NID1 and may also interact with CTTN. It plays a important role in endothelial cell capillary morphogenesis, the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs).

Synonym: Plexin Domain-Containing Protein 1, Tumor Endothelial Marker 3, Tumor Endothelial Marker 7, PLXDC1, TEM3, TEM7

Poids moléculaire: 46.5 kDa

UniProt: Q8IUK5