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PPP1R1A Protein (His tag)

PPP1R1A Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
N° du produit ABIN7318960
  • Antigène Voir toutes PPP1R1A Protéines
    PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))
    Type de proteíne
    Recombinant
    Origine
    • 4
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette PPP1R1A protéine est marqué à la His tag.
    Fonction
    Recombinant Human PPP1R1A Protein (His Tag)
    Séquence
    Met 1-Val171
    Attributs du produit
    Recombinant Human Protein Phosphatase 1 Regulatory Subunit 1A is produced by our E.coli expression system and the target gene encoding Met1-Val171 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 90 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PPP1R1A Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM DTT, 50 % Glycerol, pH 8.5.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))
    Autre désignation
    PPP1R1A (PPP1R1A Produits)
    Synonymes
    I1 Protein, IPP1 Protein, 0610038N18Rik Protein, I-1 Protein, pil Protein, IPP-1 Protein, protein phosphatase 1 regulatory inhibitor subunit 1A Protein, protein phosphatase 1, regulatory (inhibitor) subunit 1A Protein, protein phosphatase 1 regulatory inhibitor subunit 1A L homeolog Protein, PPP1R1A Protein, Ppp1r1a Protein, ppp1r1a.L Protein
    Sujet

    Background: Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.

    Synonym: Protein Phosphatase 1 Regulatory Subunit 1A, Protein Phosphatase Inhibitor 1, I-1, IPP-1, PPP1R1A, IPP1

    Poids moléculaire
    20.0 kDa
    UniProt
    Q13522
    Pathways
    Cellular Glucan Metabolic Process
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