PTP4A2 Protein (GST tag)

N° du produit ABIN7317306

Détail du produit

Antigène: PTP4A2 (Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PTP4A2 protéine est marqué à la GST tag.

Fonction: Recombinant Human PRL-2/PTP4A2 Protein (GST Tag)

Séquence: Asn 2-Gln 167

Attributs du produit: A DNA sequence encoding the human PTP4A2 isoform 1 (Q12974-1) (Asn 2-Gln 167) was fused with the GST tag at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 0.15M NaCl, 1 mM GSH, pH 7.3

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: PTP4A2 (Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2))

Autre désignation: PRL-2/PTP4A2 (PTP4A2 Produits)

Synonymes: wu:fc05f09 Protein, wu:fi84b06 Protein, zgc:101724 Protein, MGC53390 Protein, MGC80084 Protein, MGC132077 Protein, PTP4A2 Protein, ptp4a2 Protein, Prl-2 Protein, HH13 Protein, HH7-2 Protein, HU-PP-1 Protein, OV-1 Protein, PRL-2 Protein, PRL2 Protein, PTP4A Protein, PTPCAAX2 Protein, ptp-IV1a Protein, ptp-IV1b Protein, protein tyrosine phosphatase type IVA, member 2b Protein, protein tyrosine phosphatase 4a2 Protein, protein tyrosine phosphatase type IVA, member 2 Protein, protein tyrosine phosphatase type IVA, member 2 L homeolog Protein, ptp4a2b Protein, ptp4a2 Protein, PTP4A2 Protein, ptp4a2.L Protein, Ptp4a2 Protein

Sujet:

Background: PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PRL-2 phosphatases may be multifunctional enzymes with diverse roles in a variety of tissue and cell types. The phosphatase of regenerating liver (PRL) family, comprising PRL-1, PRL-2 and PRL-3, is a group of prenylated phosphatases that are candidate cancer biomarkers and therapeutic targets. PRL-1, PRL-2, and PRL-3 represent a novel class of protein-tyrosine phosphatase with a C-terminal prenylation motif. They are three closely related intracellular enzymes that possess the PTP active site signature sequence CX 5R. The PRL-2 mRNA is elevated in primary breast tumors relative to matched normal tissue, and also dramatically elevated in metastatic lymph nodes compared with primary tumors. PRL-2 plays a role in breast cancer progression. PRL-2 is a pathogenic molecule in hematopoietic malignancies and suggest its potential as a novel therapeutic target.

Synonym: Protein tyrosine phosphatase type IVA 2,PTP4A2,HU-PP-1,OV-1,PTP(CAAXII),Protein-tyrosine phosphatase 4a2,Protein-tyrosine phosphatase of regenerating liver 2,PRL-2,HH13,HH7-2,HMT,HNMT-S1,HNMT-S2,HU-PP-1,OV-1,PRL-2,PRL2,ptp-IV1a,ptp-IV1b,PTP4A,PTPCAAX2

Poids moléculaire: 45.9 kDa