QPRT Protein (His tag)
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- Antigène Voir toutes QPRT Protéines
- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette QPRT protéine est marqué à la His tag.
- Fonction
- Recombinant Human QPRT/QPRTase Protein (His Tag)
- Séquence
- Met 1-His297
- Attributs du produit
- Recombinant Human Quinolinate Phosphoribosyltransferase [Decarboxylating] is produced by our E.coli expression system and the target gene encoding Met1-His297 is expressed with a 6His tag at the N-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product QPRT Protéine
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Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (His tag)
QPRT Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (GST tag)QPRT Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
Quinolinate Phosphoribosyltransferase (QPRT) (AA 198-297) protein (GST tag)QPRT Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (Strep Tag)Crystallography grade QPRT Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-299) protein (Strep Tag)Crystallography grade QPRT Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Quinolinate Phosphoribosyltransferase (QPRT) protein (Myc-DYKDDDDK Tag)QPRT Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
- Autre désignation
- QPRT/QPRTase (QPRT Produits)
- Synonymes
- ECK0108 Protein, JW0105 Protein, VF2184 Protein, QPRTase Protein, 2410027J01Rik Protein, AI647766 Protein, quinolinate phosphoribosyltransferase Protein, nicotinate-nucleotide pyrophosphorylase Protein, nicotinate-nucleotide diphosphorylase Protein, carboxylating Protein, ECs0113 Protein, nadC Protein, VP2522 Protein, STY0167 Protein, BJE04_RS13210 Protein, QPRT Protein, Qprt Protein
- Sujet
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Background: Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quinolinic Acid (QA). The activity toward QA is slightly repressed by phosphoribosylpyrophosphate (PRPP) in both a competitive and a non-competitive manner.
Synonym: Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating], Quinolinate Phosphoribosyltransferase [Decarboxylating], QAPRTase, QPRTase, QPRT
- Poids moléculaire
- 33.0 kDa
- UniProt
- Q15274
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