REG3A Protein (Fc Tag)

N° du produit ABIN7321167

Détail du produit

Antigène: REG3A (Regenerating Islet-Derived 3 alpha (REG3A))

Type de proteíne: Recombinant

Origine: Rat

Source: HEK-293 Cells

Purification/Conjugué: Cette REG3A protéine est marqué à la Fc Tag.

Fonction: Recombinant Rat REG3A/HIP Protein (Fc Tag)

Séquence: Met1-Gln174

Attributs du produit: A DNA sequence encoding the rat REG3A (BAA04904.1) (Met1-Gln174) was expressed, fused with the Fc region of human IgG1 at the C-terminus.

Pureté: > 95 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: REG3A (Regenerating Islet-Derived 3 alpha (REG3A))

Autre désignation: REG3A/HIP (REG3A Produits)

Synonymes: HIP Protein, HIP/PAP Protein, INGAP Protein, PAP Protein, PAP-H Protein, PAP1 Protein, PBCGF Protein, REG-III Protein, REG3 Protein, AV063448 Protein, Pap2 Protein, PapII Protein, PTP Protein, REG3G Protein, regenerating family member 3 alpha Protein, regenerating islet-derived 3 alpha Protein, REG3A Protein, Reg3a Protein

Sujet:

Background: Regenerating islet-derived protein 3-alpha, also known as Regenerating islet-derived protein III-alpha, REG-3-alpha, REG3A, and HIP, is secreted protein which contains one C-type lectin domain. REG3A is constitutively expressed in intestine, and is a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It is overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. REG3A is also a stress protein involved in the control of bacterial proliferation. REG3A is down-regulated in most primary human gastric cancer cells, and might be useful in the diagnosis of gastric cancer. Additionally, REG3A is a target of beta-catenin signaling in Huh7 hepatoma cells. The REG1A and REG3A are downstream targets of the Wnt pathway during liver tumorigenesis.

Synonym: REG3A,Pap2,Reg3

Poids moléculaire: 43.4 kDa