RELT Protein (His tag)

N° du produit ABIN7317835

Détail du produit

Antigène: RELT (RELT Tumor Necrosis Factor Receptor (RELT))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette RELT protéine est marqué à la His tag.

Fonction: Recombinant Human RELT/TNFRSF19L Protein (His Tag)

Séquence: Met 1-Ala 160

Attributs du produit: A DNA sequence encoding the human RELT (NP_116260.2) extracellular domain (Met 1-Ala 160) was fused with a polyhistidine tag at the C-terminus, with 127R/G & 129R/G mutations.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: RELT (RELT Tumor Necrosis Factor Receptor (RELT))

Autre désignation: RELT/TNFRSF19L (RELT Produits)

Synonymes: E430021K24Rik Protein, Tnfrsf19l Protein, zgc:77246 Protein, TNFRSF19L Protein, TRLT Protein, RELT tumor necrosis factor receptor Protein, RELT, TNF receptor Protein, Relt Protein, relt Protein, RELT Protein

Sujet:

Background: Receptor expressed in lymphoid tissues (RELT); also known as tumor necrosis factor receptor superfamily; member 19-like (TNFRSF19L); is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1. RELT/TNFRSF19L is capable of stimulating T-cell proliferation in the presence of CD3 signaling; which suggests its regulatory role in immune response. RELT/TNFRSF19L is a type I transmembrane glycoprotein with a cysteine-rich extracellular domain; possessing significant homology to other members of the TNFR superfamily; especially TNFRSF19; DR3; OX40; and LTbeta receptor. RELT/TNFRSF19L is able to activate the NF-kappaB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. RELT/TNFRSF19L is able to activate the NF-κB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. Although the soluble form of RELT fusion protein does not inhibit the one-way mixed lymphocyte reaction; immobilized RELT/TNFRSF19L is capable of costimulating T-cell proliferation in the presence of CD3 signaling.

Synonym: Tumor necrosis factor receptor superfamily member 19L; TNFRSF19L; Receptor expressed in lymphoid tissues; RELT

Poids moléculaire: 15.7 kDa

NCBI Accession: NP_116260