ROBO2 Protein (His tag)

N° du produit ABIN7317921

Détail du produit

Antigène: ROBO2 (Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ROBO2 protéine est marqué à la His tag.

Fonction: Recombinant Human ROBO2 Protein (His Tag)

Séquence: Met 1-Pro859

Attributs du produit: A DNA sequence encoding the human ROBO2 (Q9HCK4-1) (Met1-Pro859) was expressed with a polyhistidine tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: ROBO2 (Roundabout, Axon Guidance Receptor, Homolog 2 (ROBO2))

Autre désignation: ROBO2 (ROBO2 Produits)

Synonymes: SAX3 Protein, ROBO2 Protein, CG14347 Protein, CG14348 Protein, CG5481 Protein, CG5574 Protein, CT17326 Protein, D-Robo2 Protein, D-robo2 Protein, Dmel\\CG5481 Protein, Robo 2 Protein, Robo-2 Protein, Robo2 Protein, anon-EST:Liang-1.75 Protein, clone 1.75 Protein, dRobo-2 Protein, fus4 Protein, robo-2 Protein, robo2 Protein, unp1881 Protein, 2600013A04Rik Protein, 9430089E08Rik Protein, BB097918 Protein, D230004I22Rik Protein, mKIAA1568 Protein, sax3 Protein, roundabout guidance receptor 2 Protein, roundabout 2 Protein, roundabout, axon guidance receptor, homolog 2 (Drosophila) Protein, roundabout guidance receptor 2 S homeolog Protein, ROBO2 Protein, Robo2 Protein, robo2 Protein, robo2.S Protein

Sujet:

Background: ROBO2 belongs to the ROBO family. Members of the ROBO family are a group of highly conserved transmembrane glycoproteins that make up a small subgroup of the immunoglobulin (Ig) superfamily. They are best known for their roles as receptors for the Slit family of repellent axon guidance cues. In structure, ROBOs are characterized by five C2-type Ig-like repeats, three fibronectin type III domains, a transmembrane region, and an intracellular domain with three (ROBO3) or four (ROBO1, 2) CC (conserved cytoplasmic) motifs. ROBO2 is a receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. ROBO2 also abrogates SLIT-ROBO signaling in vitro.

Synonym: KIAA1568,ROBO2,SAX3

Poids moléculaire: 94.2 kDa

Pathways: Regulation of Cell Size