SCO1 Protein (GST tag)

N° du produit ABIN7318963

Détail du produit

Antigène: SCO1 (SCO1 Cytochrome C Oxidase Assembly Protein (SCO1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SCO1 protéine est marqué à la GST tag.

Fonction: Recombinant Human SCO1/SCOD1 Protein (GST Tag)

Séquence: Gly132-Ser300

Attributs du produit: Recombinant Human Protein SCO1 Homolog Mitochondrial is produced by our E.coli expression system and the target gene encoding Gly132-Ser300 is expressed with a GST tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 50 mM PB, 1 mM DTT, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SCO1 (SCO1 Cytochrome C Oxidase Assembly Protein (SCO1))

Autre désignation: SCO1/SCOD1 (SCO1 Produits)

Synonymes: SCOD1 Protein, 2610001C07Rik Protein, D11Bwg1310e Protein, SCO1 Protein, RGD1559538 Protein, SCO1, cytochrome c oxidase assembly protein Protein, SCO1 cytochrome c oxidase assembly protein Protein, SCO1 Protein, Sco1 Protein, sco1 Protein

Sujet:

Background: Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by high rates of Oxidative Phosphorylation (OxPhos). SCO1 is thought to play a important role in cellular copper homeostasis, mitochondrial redox signaling and insertion of copper into the active site of COX. The defects of SCO1 can result in Mitochondrial Complex IV Deficiency (MT-C4D). A disorder of the mitochondrial respiratory chain has heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs.

Synonym: Protein SCO1 Homolog Mitochondrial, SCO1, SCOD1

Poids moléculaire: 20.1 kDa

UniProt: O75880

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity