SCGB1A1 Protein (His tag)

N° du produit ABIN7320758

Détail du produit

Antigène: SCGB1A1 (Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1))

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Purification/Conjugué: Cette SCGB1A1 protéine est marqué à la His tag.

Fonction: Recombinant Mouse Uteroglobin/SCGB1A1 Protein (His Tag)

Séquence: Asp22-Phe96

Attributs du produit: Recombinant Mouse Uteroglobin is produced by our Mammalian expression system and the target gene encoding Asp22-Phe96 is expressed with a 6His tag at the C-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SCGB1A1 (Secretoglobin, Family 1A, Member 1 (Uteroglobin) (SCGB1A1))

Autre désignation: Uteroglobin/SCGB1A1 (SCGB1A1 Produits)

Synonymes: CC10 Protein, CC16 Protein, CCPBP Protein, CCSP Protein, UGB Protein, UP-1 Protein, UP1 Protein, UGL Protein, PCB-BP Protein, UG Protein, Utg Protein, PCBB Protein, Ugb Protein, SCGB1A1 Protein, secretoglobin family 1A member 1 Protein, secretoglobin, family 1A, member 1 (uteroglobin) Protein, urinary protein 2 Protein, SCGB1A1 Protein, Scgb1a1 Protein, Rup2 Protein

Sujet:

Background: Uteroglobin(UG, SCGB1A1) is the founding member of the secretoglobin family of small,secreted, disulfide-bridged dimeric proteins found only in mammals. This protein is mainly expressed in lung, with anti-inflammatory/immunomodulatory properties. CCAAT/enhancer-binding proteins(C/EBPs) are the major transcription factors for the regulation of SCGB1A1 gene expression, whereas FOXA1 had a minimum effect on the transcription. Uteroglobin is a multifunctional protein with anti-inflammatory/immunomodulatory properties. Uteroglobin inhibits soluble phospholipase A(2) activity and binds and perhaps sequesters hydrophobic ligands such as progesterone, retinols, polychlorinated biphenyls, phospholipids, and prostaglandins. In addition to its anti-inflammatory activities, Uteroglobin manifests antichemotactic, antiallergic, antitumorigenic, and embryonic growth-stimulatory activities. Uteroglobin is a potential drug target. The mechanism of Uteroglobin action is likely to be even more complex as it also functions via a putative receptor-mediated pathway.

Synonym: Uteroglobin, Clara cell 17 kDa protein, Clara cell phospholipid-binding protein, CCPBP, Clara cells 10 kDa secretory protein, CC10, PCB-binding protein, Secretoglobin family 1A member 1, Scgb1a1, Cc10, Ugb,CC16,CCSP,PCB-BP,UG,UGB,Utg

Poids moléculaire: 9.2 kDa

UniProt: Q06318