SEMA6A Protein (His tag)

N° du produit ABIN7317628

Détail du produit

Antigène: SEMA6A (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette SEMA6A protéine est marqué à la His tag.

Fonction: Recombinant Human Semaphorin 6A/SEMA6A Protein (His Tag)

Séquence: Met 1-Thr 649

Attributs du produit: A DNA sequence encoding the human SEMA6A (NP_065847.1) extracellular domain (Met 1-Thr 649) was expressed, with a polyhistidine tag at the C-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SEMA6A (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A))

Autre désignation: Semaphorin 6A/SEMA6A (SEMA6A Produits)

Synonymes: fj46c12 Protein, wu:fj46c12 Protein, zgc:66106 Protein, SEMA6A Protein, HT018 Protein, SEMA Protein, SEMA6A1 Protein, SEMAQ Protein, VIA Protein, 9330158E07 Protein, A730020P05Rik Protein, AI851735 Protein, Sema6A-1 Protein, Semaq Protein, VIa Protein, b2b997Clo Protein, sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A Protein, semaphorin 6A Protein, sema6a Protein, SEMA6A Protein, Sema6a Protein

Sujet:

Background: Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.

Synonym: HT018,SEMA,SEMA6A1,SEMAQ,VIA

Poids moléculaire: 72.2 kDa

NCBI Accession: NP_065847