SERPINB4 Protein (His tag)

N° du produit ABIN7317326

Détail du produit

Antigène: SERPINB4 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette SERPINB4 protéine est marqué à la His tag.

Fonction: Recombinant Human SerpinB4 Protein (His Tag)

Séquence: Met 1-Pro 390

Attributs du produit: A DNA sequence encoding the human SERPINB4 (P48594) (Met 1-Pro 390) was expressed, with a polyhistidine tag at the N-terminus.

Pureté: > 88 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 20 % glycerol, 1 mM EDTA, 1 mM DTT

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SERPINB4 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4 (SERPINB4))

Autre désignation: SerpinB4 (SERPINB4 Produits)

Synonymes: LEUPIN Protein, PI11 Protein, SCCA-2 Protein, SCCA1 Protein, SCCA2 Protein, serpinb4 Protein, serpin family B member 4 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 4 L homeolog Protein, SERPINB4 Protein, serpinb4.L Protein

Sujet:

Background: Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells. Uracil-DNA glycosylase exists in two forms: mitochondrial uracil-DNA glycosylase 1 (UNG1) and nuclear uracil-DNA glycosylase 2 (UNG2). uracil-DNA glycosylase. This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. Defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 (HIGM5). A rare immunodeficiency syndrome characterized by normal or elevated serum IgM levels with absence of IgG, IgA, and IgE. It results in a profound susceptibility to bacterial infections.

Synonym: LEUPIN,PI11,SCCA-2,SCCA1,SCCA2

Poids moléculaire: 47.1 kDa

UniProt: P48594