SERPINB8 Protein (His tag)

N° du produit ABIN7320362

Détail du produit

Antigène: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Type de proteíne: Recombinant

Origine: Souris

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette SERPINB8 protéine est marqué à la His tag.

Fonction: Recombinant Mouse SerpinB8 Protein (His Tag)

Séquence: Met 1-Pro 374

Attributs du produit: A DNA sequence encoding the mouse SERPINB8 (NP_035589.1) (Met 1-Pro 374) was expressed,with a C-terminal polyhistidine tag.

Pureté: > 94 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SERPINB8 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 8 (SERPINB8))

Autre désignation: SerpinB8 (SERPINB8 Produits)

Synonymes: pi8 Protein, cap2 Protein, CAP-2 Protein, CAP2 Protein, NK10 Protein, Spi8 Protein, ovalbumin Protein, PI8 Protein, serpin family B member 8 Protein, serpin B8 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 8 Protein, serine (or cysteine) peptidase inhibitor, clade B, member 8 Protein, Serpinb8 Protein, SERPINB8 Protein, LOC607205 Protein, serpinb8 Protein, LOC100424017 Protein

Sujet:

Background: Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal neuroendocrine tissues, strongest SerpinB8 expression was detected in islets of Langerhans of the pancreas. Moderate SerpinB8 expression was observed in neuroendocrine cells of the thyroid, adrenal cortex, colon, and pituitary gland. In the pancreas, SerpinB8 is specifically expressed by insulin-producing beta cells, and can be used as an additional diagnostic immunohistochemical marker. Mouse SerpinB8 distribution alters during kidney regeneration, possibly to control a prohormone convertase involved in inflammation or tissue repair.

Synonym: CAP-2,CAP2,NK10,ovalbumin,Spi8

Poids moléculaire: 43.6 kDa

NCBI Accession: NP_035589