SAA2 Protein (His tag)

N° du produit ABIN7319467

Détail du produit

Antigène: SAA2 (Serum Amyloid A2 (SAA2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SAA2 protéine est marqué à la His tag.

Fonction: Recombinant Human SAA2/Serum Amyloid A2 Protein (His Tag)

Séquence: Arg19-Tyr122

Attributs du produit: Recombinant Human Serum amyloid A-2 protein is produced by our E.coli expression system and the target gene encoding Arg19-Tyr122 is expressed with a 6His tag at the N-terminus.

Pureté: > 90 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mMPB,150 mMNaCl, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SAA2 (Serum Amyloid A2 (SAA2))

Autre désignation: SAA2/Serum Amyloid A2 (SAA2 Produits)

Synonymes: SAA2 Protein, DKFZp470K0711 Protein, SAA Protein, SAA1 Protein, AW111173 Protein, Saa-2 Protein, Saa1 Protein, serum amyloid A protein Protein, serum amyloid protein A Protein, serum amyloid A2 Protein, serum amyloid A 2 Protein, serum amyloid A-2 protein Protein, LOC476879 Protein, LOC100009259 Protein, SAA2 Protein, Saa2 Protein

Sujet:

Background: Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. Increased levels of A-SAA in serum are indicative of inflammatory disease. When highly expressed, SAA can displace ApoA1 as the major apolipoprotein in HDL complexes, weakening the function of HDL as a reverse (lipid clearing) cholesterol transporter. A highly charged region of SAA2 and SAA1 (aa 36-68) contains putative fibronectin- and laminin-binding motifs. This region also binds heparin sulfate proteoglycans at mildly acidic pH and promotes aggregation of A-SAA.

Synonym: SAA, SAA2, Serum Amyloid A2

Poids moléculaire: 13.2 kDa

UniProt: P0DJI9

Pathways: Toll-Like Receptors Cascades