SPOCK1 Protein (AA 21-429) (His tag)

N° du produit ABIN7317810

Détail du produit

Antigène: SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))

Type de proteíne: Recombinant

Attributs du protein: AA 21-429

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette SPOCK1 protéine est marqué à la His tag.

Fonction: Recombinant Human SPOCK1/Testican 1 Protein (aa 21-429, His Tag)

Séquence: Met 1-Trp439

Attributs du produit: A DNA sequence encoding the human SPOCK1 (Q08629) ( Met 1-Trp439) was expressed with a C-terminal polyhistidine tag.

Pureté: > 85 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))

Autre désignation: SPOCK1/Testican 1 (SPOCK1 Produits)

Synonymes: SPOCK Protein, TESTICAN Protein, TIC1 Protein, Spock Protein, Ticn1 Protein, testican Protein, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 Protein, sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 Protein, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 Protein, SPOCK1 Protein, Spock1 Protein

Sujet:

Background: Osteonectin, also known as SPOCK1, is an extracellular heparan/chondroitin sulfate proteoglycan. Members of this family are known as testicans, also called SPOCKs. They are characterized structurally by an N-terminal testican-specific domain, a follistatin-like region, a calcium-binding domain, a thyroglobulin-like domain, and an acidic C-terminal domain with two putative glycosaminoglycan attachment sites. SPOCKs are enriched in brain and have been shown to regulate neuronal attachment and outgrowth. They contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. Osteonectin contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain. Up to now, little is known about osteonectin's function. It may play a role in cell-cell and cell-matrix interactions. Osteonectin also may contribute to various neuronal mechanisms in the central nervous system.

Synonym: SPOCK,TESTICAN,TIC1

Poids moléculaire: 48.4 kDa

UniProt: Q08629