SULT1B1 Protein (His tag)

N° du produit ABIN7317530

Détail du produit

Antigène: SULT1B1 (Sulfotransferase Family 1B Member 1 (SULT1B1))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SULT1B1 protéine est marqué à la His tag.

Fonction: Recombinant Human SULT1B1 Protein (His Tag)(Active)

Séquence: Leu 2-Ile 296

Attributs du produit: A DNA sequence encoding the human SULT1B1 (NP_055280.2) (Leu 2-Ile 296) was expressed, with a N-terminal polyhistidine tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Biological Activity Comment: Measured by its ability to transfer sulfate from PAPS to 1-Napthol.The specific activity is > 40 pmoles/min/μg.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 0.1 M NaCl, 10 % glycerol, 1 mM DTT, pH 8.0

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SULT1B1 (Sulfotransferase Family 1B Member 1 (SULT1B1))

Autre désignation: SULT1B1 (SULT1B1 Produits)

Synonymes: ST1B1 Protein, ST1B2 Protein, SULT1B2 Protein, St2b2 Protein, SULT1B Protein, cSULT1B1 Protein, MGC80677 Protein, SULT1B1 Protein, sulfotransferase family 1B member 1 Protein, sulfotransferase family 1B, member 1 Protein, sulfotransferase family cytosolic 1B member 1 Protein, sulfotransferase family 1B member 1 S homeolog Protein, sulfotransferase family, cytosolic, 1B, member 1 Protein, SULT1B1 Protein, Sult1b1 Protein, sult1b1.S Protein, sult1b1 Protein, LOC100624541 Protein

Sujet:

Background: Sulfotransferase family cytosolic 1B member 1; also known as Sulfotransferase 1B1; Sulfotransferase 1B2; Thyroid hormone sulfotransferase; SULT1B1 and ST1B2; is a cytoplasm protein which belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones; neurotransmitters; drugs; and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1B1 is highly expressed in the liver; peripheral blood leukocytes; colon (mucosal lining); small intestine (jejunum) and spleen. A lesser expression of SULT1B1 was observed in the lung; placenta and thymus. SULT1B1 catalyzes the sulfate conjugation of many hormones; neurotransmitters; drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds; and therefore their renal excretion; but it can also result in bioactivation to form active metabolites. SULT1B1 sulfates dopamine; small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones; including 3;3'-diiodothyronine; triidothyronine; reverse triiodothyronine and thyroxine.

Synonym: Sulfotransferase Family Cytosolic 1B Member 1; ST1B1; Sulfotransferase 1B1; Sulfotransferase 1B2; ST1B2; Thyroid Hormone Sulfotransferase; SULT1B1; ST1B2; SULT1B2

Poids moléculaire: 35.7 kDa

NCBI Accession: NP_055280