SULT1E1 Protein (His tag)

N° du produit ABIN7317598

Détail du produit

Antigène: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette SULT1E1 protéine est marqué à la His tag.

Fonction: Recombinant Human SULT1E1/ST1E1 Protein (His Tag)

Séquence: Asn 2-Ile 294

Attributs du produit: A DNA sequence encoding the human SULT1E1 (NP_005411.1) (Asn 2-Ile 294) was expressed, with a polyhistidine tag at the N-terminus.

Pureté: > 92 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris 0.5M NaCl, 20 % glycerol, pH 8.0

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Autre désignation: SULT1E1/ST1E1 (SULT1E1 Produits)

Synonymes: STE Protein, St1 Protein, EST Protein, ST1E1 Protein, Ste Protein, EST-1 Protein, est-1 Protein, ste Protein, sult1e1 Protein, sult1e1.S Protein, sulfotransferase family 1E member 1 Protein, sulfotransferase family 1E, estrogen-preferring, member 1 Protein, estrogen sulfotransferase Protein, sulfotransferase family 1E, member 1 Protein, sulfotransferase family 1E member 1 L homeolog Protein, Sult1e1 Protein, SULT1E1 Protein, St1 Protein, CpipJ_CPIJ012993 Protein, CpipJ_CPIJ014515 Protein, LOC482182 Protein, sult1e1.L Protein

Sujet:

Background: Estrogen sulfotransferase, also known as Sulfotransferase, estrogen-preferring, Sulfotransferase 1E1, SULT1E1 and ST1E1, is a cytoplasm enzyme which belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1E1 may control the level of the estrogen receptor by sulfurylating free estradiol. SULT1E1 maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. SULT1E1 also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated. SULT1E1 is a key enzyme in estrogen homeostasis. It plays a central role in the prevention and development of human disease.

Synonym: EST;EST-1;MGC34459;ST1E1;STE

Poids moléculaire: 36 kDa

NCBI Accession: NP_005411

Pathways: Steroid Hormone Biosynthesis