TXNL4B Protein (His tag)

N° du produit ABIN7317235

Détail du produit

Antigène: TXNL4B (Thioredoxin-Like 4B (TXNL4B))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette TXNL4B protéine est marqué à la His tag.

Fonction: Recombinant Human Dim2/TXNL4B Protein (His Tag)

Séquence: Met 1-Ile 149

Attributs du produit: A DNA sequence encoding the human TXNL4B (Q9NX01) (Met 1-Ile 149) was expressed, with a polyhistide tag at the N-terminus.

Pureté: > 92 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, 20 % glycerol, 0.1 % Tween20, 50 mM Arg, pH 7.5

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: TXNL4B (Thioredoxin-Like 4B (TXNL4B))

Autre désignation: Dim2/TXNL4B (TXNL4B Produits)

Synonymes: RGD1305127 Protein, MGC135274 Protein, MGC84953 Protein, DLP Protein, Dim2 Protein, AI595343 Protein, D530025J19Rik Protein, thioredoxin-like 4B Protein, thioredoxin like 4B Protein, thioredoxin like 4B S homeolog Protein, Txnl4b Protein, TXNL4B Protein, txnl4b Protein, txnl4b.S Protein

Sujet:

Background: Dim2, also known as TXNL4B, is a member of the DIM1 family. The Dim protein family is composed of two classes, Dim1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4/U6.U5-tri-snRNP. In spite of their biological and structural similarities, Dim1 and Dim2 proteins differ in many aspects. Dim1 bears distinctive structural motifs responsible for its interaction with other spliceosome components. Dim2 forms homodimers and contains specific domains required for its interactions with partners. This originality suggests that although both proteins are involved in pre-mRNA splicing, they are likely to be involved in different biological pathways. Dim2 roduced in E.Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids and having a molecular mass of 21.1kDa. It is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Dim2 has a vital role in pro-mRNA splicing. Dim2 is required in cell cycle progression for S/G2 transition and interacts with PRPF6 subunit of the spliceosome.

Synonym: Dim2;DLP

Poids moléculaire: 19 kDa

UniProt: Q9NX01