TWSG1 Protein (His tag)

N° du produit ABIN7319134

Détail du produit

Antigène: TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette TWSG1 protéine est marqué à la His tag.

Fonction: Recombinant Human TWSG1/TSG Protein (His Tag)

Séquence: Cys26-Phe223

Attributs du produit: Recombinant Human Twisted Gastrulation Protein Homolog 1 is produced by our Mammalian expression system and the target gene encoding Cys26-Phe223 is expressed with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))

Autre désignation: TWSG1/TSG (TWSG1 Produits)

Synonymes: TWSG1 Protein, TSG Protein, DKFZp469J051 Protein, 1810013J15Rik Protein, 9030422N06Rik Protein, AW552143 Protein, D17Ertd403e Protein, Tsg Protein, Twg Protein, fi23f01 Protein, tsg Protein, tsga Protein, twsg1 Protein, wu:fi23f01 Protein, twsg Protein, tsg1 Protein, tsgb Protein, ztsg1 Protein, twisted gastrulation BMP signaling modulator 1 Protein, twisted gastrulation homolog 1 (Drosophila) Protein, twisted gastrulation BMP signaling modulator 1a Protein, twisted gastrulation BMP signaling modulator 1 S homeolog Protein, twisted gastrulation BMP signaling modulator 1 L homeolog Protein, twisted gastrulation BMP signaling modulator 1b Protein, TWSG1 Protein, Twsg1 Protein, twsg1a Protein, twsg1.S Protein, twsg1.L Protein, twsg1b Protein

Sujet:

Background: Twisted Gastrulation Protein Homolog 1 (TWSG1) is a 22 kDa secreted protein that belongs to the twisted gastrulation protein family. Human TWSG1 is synthesized as a 223 aa precursor that contains a 25 aa signal peptide and a 198 aa mature chain. TWSG1 may be involved in dorsoventral axis formation. TWSG1 seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors.TWSG1 can inhibit BMP activity by binding directly to BMP proteins, and can act the anti-BMP function, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. TWSG1 may be an important modulator of BMP-regulated cartilage development, chondrocyte differentiation and thymocyte development.

Synonym: Twisted Gastrulation Protein Homolog 1, TWSG1, TSG

Poids moléculaire: 23.2 kDa

UniProt: Q9GZX9