GALNT3 Protein (His tag)
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- Antigène Voir toutes GALNT3 Protéines
- GALNT3 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Human Cells
- Purification/Conjugué
- Cette GALNT3 protéine est marqué à la His tag.
- Fonction
- Recombinant Human GALNT3 Protein (His Tag)
- Séquence
- Gln38-Asp633
- Attributs du produit
- Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 3 is produced by our Mammalian expression system and the target gene encoding Gln38-Asp633 is expressed with a 6His tag at the C-terminus.
- Pureté
- > 90 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GALNT3 Protéine
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Antigène
- GALNT3 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3))
- Autre désignation
- GALNT3 (GALNT3 Produits)
- Synonymes
- GalNAc-T3 Protein, HFTC Protein, HHS Protein, polypeptide N-acetylgalactosaminyltransferase 3 Protein, Galnt3 Protein, GALNT3 Protein
- Sujet
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Background: Polypeptide N-acetylgalactosaminyltransferase 3(GALNT3) belongs to the glycosyltransferase 2 family and galNAc-T subfamily. It expressed in organs that contain secretory epithelial glands and it highly expressed in pancreas, skin, kidney and testis. There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding .This protein plays a major role in regulating phosphate levels within the body (phosphate homeostasis). Among its many functions, phosphate plays a critical role in the formation and growth of bones in childhood and helps maintain bone strength in adults.
Synonym: Polypeptide N-acetylgalactosaminyltransferase 3, Polypeptide GalNAc transferase 3, GalNAc-T3, pp-GaNTase 3, Protein-UDP acetylgalactosaminyltransferase 3, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3, HFTC, HHS
- Poids moléculaire
- 69.1 kDa
- UniProt
- Q14435
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