UPP1 Protein (His tag)
-
- Antigène Voir toutes UPP1 Protéines
- UPP1 (Uridine Phosphorylase 1 (UPP1))
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette UPP1 protéine est marqué à la His tag.
- Fonction
- Recombinant Human UPP1 Protein (His Tag)
- Séquence
- Met 1-Ala173
- Attributs du produit
- Recombinant Human Uridine Phosphorylase 1 is produced by our E.coli expression system and the target gene encoding Met1-Ala173 is expressed with a 6His tag at the N-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product UPP1 Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 200 mM NaCl, 1 mM DTT, pH 8.0.
- Stock
- -20 °C
- Stockage commentaire
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Antigène
- UPP1 (Uridine Phosphorylase 1 (UPP1))
- Autre désignation
- UPP1 (UPP1 Produits)
- Synonymes
- upp1 Protein, UDRPASE Protein, UP Protein, UPASE Protein, UPP Protein, im:6911242 Protein, zgc:110755 Protein, AI325217 Protein, UPase Protein, UdRPase Protein, Up Protein, Upp Protein, uridine phosphorylase 1 Protein, uridine phosphorylase Protein, upp1 Protein, NP_RS08675 Protein, Tsp_02326 Protein, UPP1 Protein, Upp1 Protein
- Sujet
-
Background: Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues. The high level of UPP1 expression in some tumors makes it a potential prognosticfactor for some cancers, such as oral squamous cell carcinoma. UPP1 is important for the homeostatic regulation of intracellular and plasma uridine concentratios. UPP1 plays an important role in the pyrimidine salvage pathway through its catalysis of the reversible phosphorolysis of uridine to uracil.
Synonym: UPP1 Protein, Uridine Phosphorylase 1, UPP1
- Poids moléculaire
- 21.3 kDa
- UniProt
- Q86Y75
- Pathways
- Ribonucleoside Biosynthetic Process
-