WFIKKN2 Protein (His tag)

N° du produit ABIN7317436

Détail du produit

Antigène: WFIKKN2 (WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 (WFIKKN2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette WFIKKN2 protéine est marqué à la His tag.

Fonction: Recombinant Human WFIKKN2/GASP-1 Protein (His Tag)

Séquence: Met 1-His 576

Attributs du produit: A DNA sequence encoding the human WFIKKN2 (NP_783165.1) extracellular domain (Met 1-His 576) was expressed, with a polyhistidine tag at the C-terminus.

Pureté: > 96 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: WFIKKN2 (WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 2 (WFIKKN2))

Autre désignation: WFIKKN2/GASP-1 (WFIKKN2 Produits)

Synonymes: GASP-1 Protein, WFDC20B Protein, WFIKKNRP Protein, hGASP-1 Protein, 2610304F08Rik Protein, AY100450 Protein, Gasp1 Protein, WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 Protein, WFIKKN2 Protein, Wfikkn2 Protein

Sujet:

Background: WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2, also known as Growth and differentiation factor-associated serum protein 1, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein, WFIKKN-related protein, WFIKKN2 and GASP1, is a secreted protein which belongs to the WFIKKN family. WFIKKN2 contains two BPTI/Kunitz inhibitor domains, one Ig-like C2-type (immunoglobulin-like) domain, one Kazal-like domain, one NTR domain and one WAP domain. WFIKKN2 is primarily expressed in ovary, testis and brain, but not in liver. In fetal tissues, it is primarily expressed in brain, skeletal muscle, thymus and kidney. WFIKKN2 is protease-inhibitor that contains multiple distinct protease inhibitor domains. It probably has serine protease- and metalloprotease-inhibitor activity. It inhibits the biological activity of mature myostatin, but not activin. WFIKKN2 protein binds mature GDF8/myostatin and myostatin propeptide and inhibits the biological activity of myostatin.

Synonym: GASP-1;hGASP-1;WFDC20B;WFIKKNRP

Poids moléculaire: 61.4 kDa

NCBI Accession: NP_783165