ZWINT Protein (His tag)

N° du produit ABIN7319196

Détail du produit

Antigène: ZWINT (ZW10 Interactor (ZWINT))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ZWINT protéine est marqué à la His tag.

Fonction: Recombinant Human ZWINT Protein (His Tag)

Séquence: Met 1-Pro277

Attributs du produit: Recombinant Human ZW10 Interactor is produced by our E.coli expression system and the target gene encoding Met1-Pro277 is expressed with a 6His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: ZWINT (ZW10 Interactor (ZWINT))

Autre désignation: ZWINT (ZWINT Produits)

Synonymes: ZWINT Protein, HZwint-1 Protein, KNTC2AP Protein, ZWINT1 Protein, 2010007E07Rik Protein, 2600001N01Rik Protein, D10Ertd749e Protein, Zwint-1 Protein, Sip30 Protein, ZW10 interacting kinetochore protein Protein, ZW10 interactor Protein, ZWINT Protein, Zwint Protein

Sujet:

Background: ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex specifically during mitosis. ZWINT is a part of the MIS12 complex which is required for kinetochore formation and spindle checkpoint activity. In addition, ZWINT is required to target ZW10 to the kinetochore at prometaphase.

Synonym: ZW10 Interactor, ZW10-Interacting Protein 1, Zwint-1, ZWINT

Poids moléculaire: 33.4 kDa

UniProt: O95229