BACE1 Protein (AA 22-457) (His tag)
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- Antigène Voir toutes BACE1 Protéines
- BACE1 (Beta-secretase 1 (BACE1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 22-457
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette BACE1 protéine est marqué à la His tag.
- Fonction
- Human BACE-1 Protein
- Séquence
- Thr22-Thr457
- Attributs du produit
- Recombinant Human BACE-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr22-Thr457.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product BACE1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- BACE1 (Beta-secretase 1 (BACE1))
- Autre désignation
- BACE-1 (BACE1 Produits)
- Synonymes
- ASP2 Protein, BACE Protein, HSPC104 Protein, C76936 Protein, Bace Protein, MGC145931 Protein, BACE1 Protein, zgc:77409 Protein, beta-secretase 1 Protein, beta-site APP cleaving enzyme 1 Protein, beta-site APP-cleaving enzyme 1 Protein, BACE1 Protein, Bace1 Protein, bace1 Protein
- Sujet
- The beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) initiates the generation of amyloid-β (Aβ), and the amyloid cascade leading to amyloid plaque deposition, neurodegeneration, and dementia in Alzheimer's disease (AD). Clinical failures of anti-Aβ therapies in dementia stages suggest that treatment has to start in the early, asymptomatic disease states.
- Poids moléculaire
- 49.5 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_036236
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