BCMA Protein (AA 1-54) (hFc Tag)

N° du produit ABIN7273940

Protéine Recombinant BCMA exprimée dans HEK-293 Cells.

Aperçu rapide pour BCMA Protein (AA 1-54) (hFc Tag) (ABIN7273940)

Antigène: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Pureté: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Détail du produit

Attributs du protein: AA 1-54

Purification/Conjugué: Cette BCMA protéine est marqué à la hFc Tag.

Fonction: Human BCMA/TNFRSF17 Protein

Séquence: Met1-Ala54

Attributs du produit: Recombinant Human BCMA/TNFRSF17 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Met1-Ala54.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human APRIL Trimer, His Tag at 0.1ug/ml (100ul/well) on the plate. Dose response curve for Human BCMA, hFc Tag with the EC50 of 0.9ng/ml determined by ELISA (QC Test).,Human BCMA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,Loaded Human BCMA, hFc Tag on ProA-Biosensor can bind Human APRIL (Trimer), His Tag with an affinity constant of 0.24 nM as determined in BLI assay (Gator® Prime).,The purity of Human BCMA is greater than 95% as determined by SEC-HPLC.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))

Autre désignation: BCMA

Sujet: B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).

Poids moléculaire: 31.4 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.

UniProt: Q02223