CCL24 Protein (AA 27-119) (Fc Tag)

N° du produit ABIN7274048

Détail du produit

Antigène: CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))

Type de proteíne: Recombinant

Attributs du protein: AA 27-119

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CCL24 protéine est marqué à la Fc Tag.

Fonction: Human CCL24 Protein

Séquence: Val27-Cys119

Attributs du produit: Recombinant Human CCL24 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val27-Cys119.

Pureté: > 95 % as determined by Tris-Bis PAGE

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CCL24, hFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-CCL24 Antibody, hFc Tag with the EC50 of 23.2ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CCL24 (Chemokine (C-C Motif) Ligand 24 (CCL24))

Autre désignation: CCL24 (CCL24 Produits)

Synonymes: Ckb-6 Protein, MPIF-2 Protein, MPIF2 Protein, SCYA24 Protein, CKb-6 Protein, Scya24 Protein, C-C motif chemokine ligand 24 Protein, chemokine (C-C motif) ligand 24 Protein, CCL24 Protein, Ccl24 Protein

Sujet: C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fibrosis. It was found to be significantly expressed in patients with non-alcoholic steatohepatitis, in whom it regulates profibrotic processes in the liver.

Poids moléculaire: 36.5 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

UniProt: O00175

Pathways: Regulation of Actin Filament Polymerization