CCR8 Protein (AA 1-35) (Fc Tag)

N° du produit ABIN7274053

Détail du produit

Antigène: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Type de proteíne: Recombinant

Attributs du protein: AA 1-35

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CCR8 protéine est marqué à la Fc Tag.

Fonction: Human CCR8 Protein

Séquence: Met1-Lys35

Attributs du produit: Recombinant Human CCR8 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Met1-Lys35.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CCR8, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-CCR8 Antibody, hFc Tag with the EC50 of 21.3ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Autre désignation: CCR8 (CCR8 Produits)

Synonymes: CC-CKR-8 Protein, CCR-8 Protein, CDw198 Protein, CKRL1 Protein, CMKBR8 Protein, CMKBRL2 Protein, CY6 Protein, GPRCY6 Protein, TER1 Protein, C-C Protein, C-C CKR-8 Protein, CKR-8 Protein, Cmkbr8 Protein, mCCR8 Protein, C-C motif chemokine receptor 8 Protein, chemokine (C-C motif) receptor 8 Protein, CCR8 Protein, Ccr8 Protein

Sujet: CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection.

Poids moléculaire: 30.62 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.