CD79b Protein (AA 29-159) (His-Avi Tag,Biotin)

N° du produit ABIN7274235

Détail du produit

Antigène: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Type de proteíne: Recombinant

Attributs du protein: AA 29-159

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CD79b protéine est marqué à la His-Avi Tag,Biotin.

Fonction: Biotinylated Human CD79B Protein

Séquence: Ala29-Asp159

Attributs du produit: Recombinant Biotinylated Human CD79B Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala29-Asp159.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Anti-CD79B Antibody, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human CD79B, His Tag with the EC50 of 23.3ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Autre désignation: CD79B (CD79B Produits)

Synonymes: B29 Protein, Ig-beta Protein, Igb Protein, Igbeta Protein, AGM6 Protein, IGB Protein, CD79B antigen Protein, CD79b molecule Protein, Cd79b Protein, CD79B Protein

Sujet: CD79B (also known as B29, Ig beta and B cell antigen receptor complex-associated protein beta-chain) is a 36-40 kDa member of the Ig-Superfamily. It is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

Poids moléculaire: 18.1 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result.

Pathways: BCR Signaling