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CD93 Protein (CD93) (AA 22-580) (Fc Tag)

CD93 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274268
  • Antigène Voir toutes CD93 Protéines
    CD93
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 22-580
    Origine
    • 14
    • 3
    • 2
    Humain
    Source
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette CD93 protéine est marqué à la Fc Tag.
    Fonction
    Human CD93/C1q R1 Protein
    Séquence
    Thr22-Lys580
    Attributs du produit
    Recombinant Human CD93/C1q R1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Thr22-Lys580.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human IGFBP-7, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Human CD93, hFc Tag with the EC50 of 2.6μg/ml determined by ELISA. See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CD93
    Autre désignation
    CD93 (CD93 Produits)
    Synonymes
    6030404G09Rik Protein, AA145088 Protein, AA4.1 Protein, AW555904 Protein, C1qr1 Protein, C1qrp Protein, Ly68 Protein, C1QR1 Protein, C1qR(P) Protein, C1qRP Protein, CDw93 Protein, ECSM3 Protein, MXRA4 Protein, dJ737E23.1 Protein, C1qRp Protein, CD93 antigen Protein, CD93 molecule Protein, Cd93 Protein, CD93 Protein
    Sujet
    CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels.
    Poids moléculaire
    85 kDa. Due to glycosylation, the protein migrates to 115-120 kDa based on Tris-Bis PAGE result.
    UniProt
    Q9NPY3
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