CD1a Protein (CD1a) (AA 19-300) (His tag)

N° du produit ABIN7274279

Détail du produit

Antigène: CD1a

Type de proteíne: Recombinant

Attributs du protein: AA 19-300

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CD1a protéine est marqué à la His tag.

Fonction: Human CD1A Protein

Séquence: Asp19-Val300

Attributs du produit: Recombinant Human CD1A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp19-Val300.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CD1a

Autre désignation: CD1A (CD1a Produits)

Synonymes: CD1 Protein, FCB6 Protein, HTA1 Protein, R4 Protein, T6 Protein, CD1A Protein, CD1a molecule Protein, CD1 antigen Protein, T-cell surface glycoprotein CD1a Protein, CD1A Protein, CD1.1 Protein, LOC100156095 Protein, LOC101111409 Protein

Sujet: CD1 proteins are a family of major histocompatibility complex (MHC) class I-like antigen-presenting molecules that present lipids to T cells. The cytoplasmic tails (CTs) of all human CD1 isoforms, with the exception of CD1a, contain tyrosine-based sorting motifs, responsible for the internalization of proteins by the clathrin-mediated pathway. CD1a closer to MHC class I in its trafficking and potential antigen-loading compartments among CD1 isoforms.

Poids moléculaire: 33.3 kDa. Due to glycosylation, the protein migrates to 48-53 kDa and 13-14 kDa based on Tris-Bis PAGE result.

NCBI Accession: NP_001754

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process