CTGF Protein (AA 27-349) (Fc Tag)

N° du produit ABIN7274341

Détail du produit

Antigène: CTGF (Connective Tissue Growth Factor (CTGF))

Type de proteíne: Recombinant

Attributs du protein: AA 27-349

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CTGF protéine est marqué à la Fc Tag.

Fonction: Human CTGF/CCN2 Protein

Séquence: Gln27-Ala349

Attributs du produit: Recombinant Human CTGF/CCN2 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln27-Ala349.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CTGF, hFc Tag at 0.2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-CTGF Antibody, hFc Tag with the EC50 of 14.2ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CTGF (Connective Tissue Growth Factor (CTGF))

Autre désignation: CTGF (CTGF Produits)

Synonymes: Ccn2 Protein, Fisp12 Protein, Hcs24 Protein, fisp-12 Protein, CCN2 Protein, HCS24 Protein, IGFBP8 Protein, NOV2 Protein, CTGRP Protein, ctgf Protein, hm:zeh1559 Protein, si:dkey-266k12.4 Protein, wu:fl25c03 Protein, zeh1559 Protein, zgc:136644 Protein, XCTGF Protein, ccn2 Protein, nov2 Protein, hcs24 Protein, igfbp8 Protein, CTGF Protein, si:ch211-173b8.2 Protein, connective tissue growth factor Protein, connective tissue growth factor a Protein, connective tissue growth factor L homeolog Protein, connective tissue growth factor b Protein, Ctgf Protein, CTGF Protein, ctgfa Protein, ctgf.L Protein, ctgf Protein, ctgfb Protein

Sujet: Connective tissue growth factor (CTGF) is a member of the CCN matricellular protein family, consisting of four domains, that regulates the signaling of other growth factors and promotes kidney fibrosis.CTGF can simultaneously interact with several factors with its four domains. The microenvironment differs depending on the types of cells and tissues and differentiation stages of these cells.

Poids moléculaire: 61.77 kDa. Due to glycosylation, the protein migrates to 50-55 kDa and 62-72 kDa based on Tris-Bis PAGE result.

UniProt: Q5M8T4

Pathways: Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding