CLEC4A Protein (AA 70-238) (Fc Tag)

N° du produit ABIN7274364

Détail du produit

Antigène: CLEC4A (C-Type Lectin Domain Family 4, Member A (CLEC4A))

Type de proteíne: Recombinant

Attributs du protein: AA 70-238

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette CLEC4A protéine est marqué à la Fc Tag.

Fonction: Mouse CLEC4A/DCIR Protein

Séquence: Gln70-Leu238

Attributs du produit: Recombinant Mouse CLEC4A/DCIR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln70-Leu238.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CLEC4A (C-Type Lectin Domain Family 4, Member A (CLEC4A))

Autre désignation: CLEC4A (CLEC4A Produits)

Synonymes: CLEC4A Protein, CLECSF6 Protein, DCIR Protein, DDB27 Protein, LLIR Protein, Clecsf6 Protein, Dcir1 Protein, Clec4a Protein, zinc finger protein 705A Protein, C-type lectin domain family 4 member A Protein, C-type lectin domain family 4, member A Protein, C-type lectin domain family 4, member a2 Protein, ZNF705A Protein, CLEC4A Protein, Clec4a Protein, Clec4a2 Protein

Sujet: Clec4a has been reported to be an immune suppressor of dendritic cells (DCs), but its potential role in cancer therapy remains to be elucidated. silencing of Clec4a2 expression via skin delivery of shRNA produces an effective antitumor response and that Clec4a2 shRNA may have therapeutic potential as an adjuvant for cancer immunotherapy.

Poids moléculaire: 46.3 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Tris-Bis PAGE result.

UniProt: Q9QZ15