Desmoglein 2 Protein (DSG2) (AA 50-609) (His tag)

N° du produit ABIN7274500

Détail du produit

Antigène: Desmoglein 2 (DSG2)

Type de proteíne: Recombinant

Attributs du protein: AA 50-609

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Desmoglein 2 protéine est marqué à la His tag.

Fonction: Human DSG-2/Desmoglein-2 Protein

Séquence: Ala50-Gly609

Attributs du produit: Recombinant Human DSG-2/Desmoglein-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala50-Gly609.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human DSG-2, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 0.17ug/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Desmoglein 2 (DSG2)

Autre désignation: DSG-2 (DSG2 Produits)

Synonymes: DSG2 Protein, dsc Protein, dsga Protein, si:dkeyp-51f12.6 Protein, wu:fj23f02 Protein, ARVC10 Protein, ARVD10 Protein, CDHF5 Protein, CMD1BB Protein, HDGC Protein, AA408168 Protein, D18Ertd293e Protein, desmoglein 2 Protein, desmoglein 2, tandem duplicate 1 Protein, DSG2 Protein, dsg2.1 Protein, dsg2 Protein, Dsg2 Protein

Sujet: Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.

Poids moléculaire: 63.6 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result.

UniProt: Q14126

Pathways: Cell-Cell Junction Organization