Desmoglein 3 Protein (DSG3) (AA 50-617) (His tag)

N° du produit ABIN7274503

Détail du produit

Antigène: Desmoglein 3 (DSG3)

Type de proteíne: Recombinant

Attributs du protein: AA 50-617

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette Desmoglein 3 protéine est marqué à la His tag.

Fonction: Mouse DSG3 Protein

Séquence: Glu50-Pro617

Attributs du produit: Recombinant Mouse DSG3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu50-Pro617.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Desmoglein 3 (DSG3)

Autre désignation: DSG3 (DSG3 Produits)

Synonymes: DSG3 Protein, CDHF6 Protein, PVA Protein, bal Protein, balding Protein, desmoglein 3 Protein, DSG3 Protein, Dsg3 Protein

Sujet: To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC.

Poids moléculaire: 64.3 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Tris-Bis PAGE result.