AIMP1
(Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
Type de proteíne
Recombinant
Attributs du protein
AA 2-312
Origine
Humain
Source
Escherichia coli (E. coli)
Purification/Conjugué
Cette AIMP1 protéine est marqué à la His tag.
Fonction
Human EMAP-II/AIMP1 Protein
Séquence
Ala2-Lys312
Attributs du produit
Recombinant Human EMAP-II/AIMP1 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ala2-Lys312.
Pureté
> 95 % as determined by Tris-Bis PAGE
Stérilité
0.22 μm filtered
niveau d'endotoxine
Less than 1EU per μg by the LAL method.
Biological Activity Comment
Immobilized Human EMAP-II, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-EMAP-II Antibody, hFc Tag with the EC50 of 0.18ug/ml determined by ELISA. See testing image for detail.
Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 10 % Glycerol ( pH 8.0).
Stock
-80 °C
Stockage commentaire
Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Date de péremption
12 months
Antigène
AIMP1
(Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))
The potent antiangiogenic and proinflammatory protein Endothelial Monocyte Activating Polypeptide II (EMAP II) has been described as a mediator of pulmonary vascular and alveolar formation and its expression is inversely related to the periods of vascularization and alveolarization in the developing lung. Hence the study of EMAP II could play a vital role in studying and devising appropriate therapeutics for diseases of aberrant lung development, such as BPD.
Poids moléculaire
35.4 kDa. The protein migrates to 40-45 kDa based on Tris-Bis PAGE result.