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FBLN3 Protein (AA 18-493) (His tag)

FBLN3 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274512
  • Antigène Voir toutes FBLN3 Protéines
    FBLN3 (Fibulin 3 (FBLN3))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 18-493
    Origine
    • 8
    • 4
    • 3
    • 1
    • 1
    Humain
    Source
    • 5
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette FBLN3 protéine est marqué à la His tag.
    Fonction
    Human EFEMP1 Protein
    Séquence
    Gln18-Phe493
    Attributs du produit
    Recombinant Human EFEMP1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gln18-Phe493.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human EFEMP1, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Anti-EFEMP1 Antibody, hFc Tag with the EC50 of 35.1ng/ml determined by ELISA. See testing image for detail.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    FBLN3 (Fibulin 3 (FBLN3))
    Autre désignation
    EFEMP1 (FBLN3 Produits)
    Synonymes
    DHRD Protein, DRAD Protein, FBLN3 Protein, FBNL Protein, FIBL-3 Protein, MLVT Protein, MTLV Protein, S1-5 Protein, T16 Protein, EGF containing fibulin like extracellular matrix protein 1 Protein, EGF-containing fibulin-like extracellular matrix protein 1 Protein, epidermal growth factor-containing fibulin-like extracellular matrix protein 1 Protein, EFEMP1 Protein, Efemp1 Protein
    Sujet
    Transversalis fascia EFEMP1, TIMP3 and ELN expressions were decreased, but MMP9 expression was increased in IH patients compared with controls. In IH patients, EFEMP1 was not correlated with TIMP3, but positively correlated with ELN and negatively correlated with MMP9, TIMP3 negatively correlated with MMP9, but positively correlated with ELN.In addition, EFEMP1 suppressed L929 cell migration and invasion.
    Poids moléculaire
    53.9 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.
    Pathways
    EGFR Signaling Pathway
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