FBLN3 Protein (AA 18-493) (His tag)

N° du produit ABIN7274512

Détail du produit

Antigène: FBLN3 (Fibulin 3 (FBLN3))

Type de proteíne: Recombinant

Attributs du protein: AA 18-493

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette FBLN3 protéine est marqué à la His tag.

Fonction: Human EFEMP1 Protein

Séquence: Gln18-Phe493

Attributs du produit: Recombinant Human EFEMP1 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gln18-Phe493.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human EFEMP1, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Anti-EFEMP1 Antibody, hFc Tag with the EC50 of 35.1ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: FBLN3 (Fibulin 3 (FBLN3))

Autre désignation: EFEMP1 (FBLN3 Produits)

Synonymes: DHRD Protein, DRAD Protein, FBLN3 Protein, FBNL Protein, FIBL-3 Protein, MLVT Protein, MTLV Protein, S1-5 Protein, T16 Protein, EGF containing fibulin like extracellular matrix protein 1 Protein, EGF-containing fibulin-like extracellular matrix protein 1 Protein, epidermal growth factor-containing fibulin-like extracellular matrix protein 1 Protein, EFEMP1 Protein, Efemp1 Protein

Sujet: Transversalis fascia EFEMP1, TIMP3 and ELN expressions were decreased, but MMP9 expression was increased in IH patients compared with controls. In IH patients, EFEMP1 was not correlated with TIMP3, but positively correlated with ELN and negatively correlated with MMP9, TIMP3 negatively correlated with MMP9, but positively correlated with ELN.In addition, EFEMP1 suppressed L929 cell migration and invasion.

Poids moléculaire: 53.9 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.

Pathways: EGFR Signaling Pathway