Selectin E/CD62e Protein (His-Avi Tag,Biotin)
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- Antigène Voir toutes Selectin E/CD62e (SELE) Protéines
- Selectin E/CD62e (SELE) (Selectin E (SELE))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Selectin E/CD62e protéine est marqué à la His-Avi Tag,Biotin.
- Séquence
- Trp22-Pro556
- Pureté
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Biotinylated Human E-Selectin at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-E-Selectin Antibody, hFc Tag with the EC50 of 7.8ng/ml determined by ELISA. See testing image for detail.
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- Discover our top product SELE Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Selectin E/CD62e (SELE) (Selectin E (SELE))
- Autre désignation
- E-Selectin (SELE Produits)
- Synonymes
- SELE Protein, CD62E Protein, ELAM Protein, ELAM1 Protein, ESEL Protein, LECAM2 Protein, E-selectin Protein, Elam Protein, selectin E Protein, selectin, endothelial cell Protein, SELE Protein, Sele Protein
- Sujet
- CD62E, ELAM, ELAM1, ESEL, E-Selectin, LECAM2, SELE, selectin E, RP1-117P20.2,E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107 - 115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.
- Poids moléculaire
- 61.6 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on Tris-Bis PAGE result.
- UniProt
- P16581
- Pathways
- Thromboxane A2 Receptor Signaling
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