FAM3D Protein (AA 26-224) (Fc Tag)
-
- Antigène Voir toutes FAM3D Protéines
- FAM3D (Family with Sequence Similarity 3, Member D (FAM3D))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 26-224
-
Origine
- Humain
-
Source
- HEK-293 Cells
- Purification/Conjugué
- Cette FAM3D protéine est marqué à la Fc Tag.
- Fonction
- Human FAM3D Protein
- Séquence
- Tyr26-Phe224
- Attributs du produit
- Recombinant Human FAM3D Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Tyr26-Phe224.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product FAM3D Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- FAM3D (Family with Sequence Similarity 3, Member D (FAM3D))
- Autre désignation
- FAM3D (FAM3D Produits)
- Synonymes
- Oit1 Protein, EF7 Protein, OIT1 Protein, 2310076N21Rik Protein, AV067083 Protein, EF-7 Protein, Fam3d Protein, family with sequence similarity 3, member D Protein, family with sequence similarity 3 member D Protein, oncoprotein induced transcript 1 Protein, Fam3d Protein, FAM3D Protein, Oit1 Protein
- Sujet
- The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly expressed in mouse gastrointestinal tract. Here, we demonstrate that deficiency in Fam3D is associated with impaired integrity of colonic mucosa, increased epithelial hyper-proliferation, reduced anti-microbial peptide production and increased sensitivity to chemically induced colitis associated with high incidence of cancer.
- Poids moléculaire
- 48.7 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
- UniProt
- Q96BQ1
-