GUCY2C Protein (AA 24-430) (Fc Tag)

N° du produit ABIN7274715

Détail du produit

Antigène: GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))

Type de proteíne: Recombinant

Attributs du protein: AA 24-430

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GUCY2C protéine est marqué à la Fc Tag.

Fonction: Human GUCY2C/Guanylyl cyclase C Protein

Séquence: Ser24-Gln430

Attributs du produit: Recombinant Human GUCY2C/Guanylyl cyclase C Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser24-Gln430.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human GUCY2C, hFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-GUCY2C Antibody, hFc Tag with the EC50 of 15.0ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))

Autre désignation: GUCY2C (GUCY2C Produits)

Synonymes: DIAR6 Protein, GUC2C Protein, MECIL Protein, MUCIL Protein, STAR Protein, AI893437 Protein, GC-C Protein, Gcc Protein, GCC Protein, gucy2c-A Protein, GUCY2C Protein, Gucy2c Protein, guanylate cyclase 2C Protein, guanylate cyclase 2c Protein, guanylate cyclase 2C L homeolog Protein, GUCY2C Protein, Gucy2c Protein, gucy2c.L Protein, gucy2c Protein

Sujet: Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.

Poids moléculaire: 72.8 kDa. Due to glycosylation, the protein migrates to 85-115 kDa based on Tris-Bis PAGE result.