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Osteoactivin Protein (GPNMB) (AA 23-486) (His tag)

Protéine Recombinant Osteoactivin exprimée dans HEK-293 Cells.
N° du produit ABIN7274753

Aperçu rapide pour Osteoactivin Protein (GPNMB) (AA 23-486) (His tag) (ABIN7274753)

Antigène

Voir toutes Osteoactivin (GPNMB) Protéines
Osteoactivin (GPNMB)

Type de proteíne

Recombinant

Origine

  • 15
  • 3
Humain

Source

  • 9
  • 3
  • 3
  • 1
  • 1
  • 1
HEK-293 Cells

Pureté

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Attributs du protein

    AA 23-486

    Purification/Conjugué

    Cette Osteoactivin protéine est marqué à la His tag.

    Fonction

    Human Osteoactivin/GPNMB Protein

    Séquence

    Lys23-Asn486

    Attributs du produit

    Recombinant Human Osteoactivin/GPNMB Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys23-Asn486.

    Stérilité

    0.22 μm filtered

    niveau d'endotoxine

    Less than 1EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    Osteoactivin (GPNMB)

    Autre désignation

    Osteoactivin

    Sujet

    GPNMB is highly expressed in macrophages and microglia, which are cells involved with innate immune response in the periphery and the brain, respectively. Some studies have shown increased levels of GPNMB in pro-inflammatory conditions, such as LPS treatment, and in pathological conditions, such as neurodegenerative diseases and cancer.

    Poids moléculaire

    53.1 kDa. Due to glycosylation, the protein migrates to 78-98 kDa based on Tris-Bis PAGE result.

    NCBI Accession

    NP_002501
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