Osteoactivin Protein (GPNMB) (AA 23-486) (His tag)
Aperçu rapide pour Osteoactivin Protein (GPNMB) (AA 23-486) (His tag) (ABIN7274753)
Antigène
Voir toutes Osteoactivin (GPNMB) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 23-486
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Purification/Conjugué
- Cette Osteoactivin protéine est marqué à la His tag.
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Fonction
- Human Osteoactivin/GPNMB Protein
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Séquence
- Lys23-Asn486
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Attributs du produit
- Recombinant Human Osteoactivin/GPNMB Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Lys23-Asn486.
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Stérilité
- 0.22 μm filtered
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niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Date de péremption
- 12 months
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- Osteoactivin (GPNMB)
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Autre désignation
- Osteoactivin
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Sujet
- GPNMB is highly expressed in macrophages and microglia, which are cells involved with innate immune response in the periphery and the brain, respectively. Some studies have shown increased levels of GPNMB in pro-inflammatory conditions, such as LPS treatment, and in pathological conditions, such as neurodegenerative diseases and cancer.
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Poids moléculaire
- 53.1 kDa. Due to glycosylation, the protein migrates to 78-98 kDa based on Tris-Bis PAGE result.
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NCBI Accession
- NP_002501
Antigène
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