×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
Osteoactivin Protein (GPNMB) (AA 22-474) (His tag)
GPNMB
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
N° du produit ABIN5854811
Détail du produit
(cache)
Antigène
Voir toutes Osteoactivin (GPNMB) Protéines
Osteoactivin (GPNMB)
Type de proteíne
Recombinant
Attributs du protein
AA 22-474
Origine
Toutes les origines à travers Osteoactivin Protéines
Humain
Source
Toutes les sources à travers Osteoactivin Protéines
Baculovirus infected Insect Cells
Purification/Conjugué
Cette Osteoactivin protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
ADPAKRFHDV LGNERPSAYM REHNQLNGWS SDENDWNEKL YPVWKRGDMR WKNSWKGGRV QAVLTSDSPA LVGSNITFAV NLIFPRCQKE DANGNIVYEK NCRNEAGLSA DPYVYNWTAW SEDSDGENGT GQSHHNVFPD GKPFPHHPGW RRWNFIYVFH TLGQYFQKLG RCSVRVSVNT ANVTLGPQLM EVTVYRRHGR AYVPIAQVKD VYVVTDQIPV FVTMFQKNDR NSSDETFLKD LPIMFDVLIH DPSHFLNYST INYKWSFGDN TGLFVSTNHT VNHTYVLNGT FSLNLTVKAA APGPCPPPPP PPRPSKPTPS LGPAGDNPLE LSRIPDENCQ INRYGHFQAT ITIVEGILEV NIIQMTDVLM PVPWPESSLI DFVVTCQGSI PTEVCTIISD PTCEITQNTV CSPVDVDEMC LLTVRRTFNG SGTYCVNLTL GDDTSLALTS TLISVPHHHH HH
Pureté
> 90 % by SDS - PAGE
niveau d'endotoxine
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Top Product
Discover our top product GPNMB Protéine
Alternatives
(show)
Information d'application
(cache)
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
(cache)
Antigène
Osteoactivin (GPNMB)
Autre désignation
GPNMB (GPNMB Produits )
Synonymes
HGFIN Protein, NMB Protein, DC-HIL Protein, Dchil Protein, ipd Protein, glycoprotein nmb Protein, glycoprotein (transmembrane) nmb Protein, glycoprotein nmb L homeolog Protein, Gpnmb Protein, GPNMB Protein, gpnmb.L Protein
Sujet
GPNMB, also known as glycoprotein nmb, is a transmembrane glycoprotein that is expressed in numerous cells, including osteoclasts, macrophages, dendritic cells, and tumor cells. It shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. This protein participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages. It may be involved in growth delay and reduction of metastatic potential. Recombinant human GPNMB protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
51.8kDa (462aa) 50-70KDa (SDS-PAGE under reducing conditions.)
NCBI Accession
NP_002501
UniProt
Q14956
Vus récemment
(cache)