IL17RC Protein (AA 21-467) (Fc Tag)

N° du produit ABIN7274895

Détail du produit

Antigène: IL17RC (Interleukin 17 Receptor C (IL17RC))

Type de proteíne: Recombinant

Attributs du protein: AA 21-467

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IL17RC protéine est marqué à la Fc Tag.

Fonction: Human IL-17Rc Protein

Séquence: Leu21-Arg467

Attributs du produit: Recombinant Human IL-17Rc Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu21-Arg467.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human IL-17A, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-17Rc, hFc Tag with the EC50 of 43.5ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: IL17RC (Interleukin 17 Receptor C (IL17RC))

Autre désignation: IL-17Rc (IL17RC Produits)

Synonymes: IL17-RL Protein, IL17RL Protein, 1110025H02Rik Protein, Gm19850 Protein, IL-17RC Protein, IL17-RC Protein, Il17rl Protein, interleukin 17 receptor C Protein, Il17rc Protein, IL17RC Protein

Sujet: IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.

Poids moléculaire: 76.2 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result.

NCBI Accession: NP_703190