IL17F Protein (AA 31-163) (His tag)

N° du produit ABIN7275002

Détail du produit

Antigène: IL17F (Interleukin 17F (IL17F))

Type de proteíne: Recombinant

Attributs du protein: AA 31-163

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IL17F protéine est marqué à la His tag.

Fonction: Human IL-17F Protein

Séquence: Arg31-Gln163

Attributs du produit: Recombinant Human IL-17F Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg31-Gln163.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human IL-17F, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-17R alpha, hFc Tag with the EC50 of 1.76μg/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: IL17F (Interleukin 17F (IL17F))

Autre désignation: IL-17F (IL17F Produits)

Synonymes: CANDF6 Protein, IL-17F Protein, ML-1 Protein, ML1 Protein, C87042 Protein, IL17F Protein, interleukin 17F Protein, IL17F Protein, Il17f Protein

Sujet: The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus.IL-17F is ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover.

Poids moléculaire: 17.5 kDa. Due to glycosylation, the protein migrates to 23-28 kDa based on Tris-Bis PAGE result.

UniProt: Q96PD4

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity