KIR3DL2
(Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 2 (KIR3DL2))
Type de proteíne
Recombinant
Attributs du protein
AA 22-339
Origine
Humain
Source
HEK-293 Cells
Purification/Conjugué
Cette KIR3DL2 protéine est marqué à la His-Avi Tag.
Fonction
Human KIR3DL2 Protein
Séquence
Leu22-Leu339
Attributs du produit
Recombinant Human KIR3DL2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Leu22-Leu339.
Pureté
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Stérilité
0.22 μm filtered
niveau d'endotoxine
Less than 1EU per μg by the LAL method.
Biological Activity Comment
Immobilized Human KIR3DL2, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-KIR3DL2 Antibody, hFc Tag with the EC50 of 0.47μg/ml determined by ELISA. See testing image for detail.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
Buffer
Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
Stock
-20 °C,-80 °C
Stockage commentaire
-20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Date de péremption
12 months
Antigène
KIR3DL2
(Killer Cell Immunoglobulin-Like Receptor, three Domains, Long Cytoplasmic Tail, 2 (KIR3DL2))
CD158K Protein, NKAT-4 Protein, NKAT4 Protein, NKAT4B Protein, p140 Protein, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 Protein, KIR3DL2 Protein
Sujet
KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linked homodimer. Each chain is composed of three immunoglobulin-like domains and a long cytoplasmic tail containing two immunoreceptor tyrosine-based inhibitory motifs.
Poids moléculaire
37.9 kDa. Due to glycosylation, the protein migrates to 40-70 kDa based on Tris-Bis PAGE result.