L1CAM Protein (AA 20-1123) (His tag)

N° du produit ABIN7275127

Détail du produit

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Type de proteíne: Recombinant

Attributs du protein: AA 20-1123

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette L1CAM protéine est marqué à la His tag.

Fonction: Mouse L1CAM Protein

Séquence: Ile20-Glu1123

Attributs du produit: Recombinant Mouse L1CAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile20-Glu1123.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Autre désignation: L1CAM (L1CAM Produits)

Synonymes: l1cam-a Protein, CAML1 Protein, CD171 Protein, HSAS Protein, HSAS1 Protein, MASA Protein, MIC5 Protein, N-CAM-L1 Protein, N-CAML1 Protein, NCAM-L1 Protein, S10 Protein, SPG1 Protein, L1 Protein, Hsas Protein, Hyd Protein, NCAML1 Protein, L1 cell adhesion molecule S homeolog Protein, L1 cell adhesion molecule Protein, l1cam.S Protein, L1CAM Protein, L1cam Protein

Sujet: L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers.

Poids moléculaire: 125.4 kDa. Due to glycosylation, the protein migrates to 160-180 kDa based on Tris-Bis PAGE result.

UniProt: P11627

Pathways: Synaptic Membrane