LYPD3 Protein (AA 31-286) (His tag)

N° du produit ABIN7275199

Détail du produit

Antigène: LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))

Type de proteíne: Recombinant

Attributs du protein: AA 31-286

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette LYPD3 protéine est marqué à la His tag.

Fonction: Human LYPD3 Protein

Séquence: Leu31-His286

Attributs du produit: Recombinant Human LYPD3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu31-His286.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human LYPD3, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-LYPD3 Ab., hFc Tag with the EC50 of 11.6ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))

Autre désignation: LYPD3 (LYPD3 Produits)

Synonymes: LYPD3 Protein, MGC139913 Protein, C4.4A Protein, 2310061G07Rik Protein, C4.4a Protein, LY6/PLAUR domain containing 3 Protein, Ly6/Plaur domain containing 3 Protein, LYPD3 Protein, Lypd3 Protein

Sujet: Aberrant expression of LYPD3 plays an oncogenic role in several types of cancer. LYPD3 was highly expressed in LUAD tumor compared with paracancerous tissues.Furthermore, the expression of LYPD3 was able to be regulated by the methylation in LYPD3 promoter region, which was positively associated with the overall survival. LYPD3 might affect the clinical manifestations of LUAD by regulating the P53 signaling pathway.

Poids moléculaire: 27.8 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

UniProt: O95274