Lrig1 Protein (AA 34-792) (His tag)

N° du produit ABIN7275204

Détail du produit

Antigène: Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))

Type de proteíne: Recombinant

Attributs du protein: AA 34-792

Origine: Cynomolgus

Source: HEK-293 Cells

Purification/Conjugué: Cette Lrig1 protéine est marqué à la His tag.

Fonction: Cynomolgus LRIG1 Protein

Séquence: Ala34-Thr792

Attributs du produit: Recombinant Cynomolgus LRIG1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala34-Thr792.

Pureté: > 95 % as determined by Tris-Bis PAGE

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Cynomolgus LRIG1, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-LRIG1 Antibody, hFc Tag with the EC50 of 10.8ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))

Autre désignation: LRIG1 (Lrig1 Produits)

Synonymes: LIG-1 Protein, LIG1 Protein, D6Bwg0781e Protein, Img Protein, leucine rich repeats and immunoglobulin like domains 1 Protein, leucine-rich repeats and immunoglobulin-like domains 1 Protein, LRIG1 Protein, Lrig1 Protein

Sujet: The leucine-rich repeats and immunoglobulin-like domains (LRIG)-1 is a tumor suppressor gene that belongs to the LRIG family. LRIG1 expression has prognostic significance in various human cancers. Somatic mutations, which are associated with a certain rate of response to targeted therapies, are ubiquitously found in human non-small cell lung cancer (NSCLC). LRIG1 was an independent prognostic factor for OS of NSCLC patients. LRIG1 in combination with other clinicopathological risk factors was a stronger prognostic model than clinicopathological risk factors alone.

Poids moléculaire: 84.16 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.

UniProt: A0A2K5V8J9